HGH Fragment 176-191

Growth Hormone (GH) Questions
-What is growth hormone?
-How does growth hormone work?
-How is natural growth hormone released?

Synthetic Growth Hormone
-What is Human Growth Hormone (HGH) Fragment 176-191?
-How much Human Growth Hormone (HGH) Fragment 176-191 should be used?
-How long should Human Growth Hormone (HGH) Fragment 176-191 be used?
-What is a typical protocol for Human Growth Hormone (HGH) Fragment 176-191?
-What are some of the possible side effects with Human Growth Hormone (HGH) Fragment 176-191?
-Should food be consumed before or after the injection of Human Growth Hormone (HGH) Fragment 176-191?

See below for the answers to the above questions

What is growth hormone?
Synthetic Growth Hormone (Somatropin) is an artificially created hormone (made up of a sequence of 191 amino acids) that is identical to the one found in humans. Some common names of synthetic growth hormone include: Genotropin by Genentech, Humatrope by Eli Lilly, Nutropin by Genentech and Saizen by Serono. While many companies are capable of generating growth hormone not all of the companies are capable of creating the correct structure that is identical to naturally occurring growth hormone. The structure determines the strength with which the growth hormone molecule binds to a receptor which will in turn affect the “strength” of the events leading to protein transcription, metabolism, IGF-1 creation, etc. It is this inconsistency that accounts in part for the differences in effectiveness of various produced synthetic growth hormone. Synthetic growth hormone is not really true or natural growth hormone. It was manufactured in a laboratory and not by your pituitary.

Naturally produced Growth Hormone is produced in the anterior pituitary. It is made up of a blend of amino acids with the majority of them being the 191 amino acid variety.

How does growth hormone work?
Growth hormone in the body is released in a pulsating fashion. It has been demonstrated that this pattern promotes growth. The pituitary is capable of rather quickly synthesizing very large amounts of growth hormone which it stores in both a finished and unfinished form. Adults rarely experience growth hormone pulses that completely deplete these stores. As we get older we do not lose the ability to create and store large amounts of growth hormone, rather we experience a diminished capacity to instruct their release. The growth hormone pulse is measured in a wave with the trough being the “off” or non-secretion of growth hormone and the crest being the “on” or highest point during growth hormone secretion.

The volume of growth hormone that is released in the body cannot be properly compared to the administration of synthetic growth hormone for the reason that a set of behavioral characteristics associated with natural growth hormone differ from those of synthetic growth hormone. Therefore attempting to find a natural growth hormone to a synthetic growth hormone equivalency is not very productive because in the end what is probably most important is: The quantity and quality of intracellular signaling events and the degree to which growth hormone stimulates autocrine/paracrine (locally produced/locally used) muscle IGF-1 & post-exercise its splice variant MGF.

What is Human Growth Hormone (HGH) Fragment 176-191?
The HGH Fragment is a modified form of amino acids 176-191 at the C-terminal region of the human growth hormone (HGH). Studies have shown that it works by mimicking the way natural HGH regulates fat metabolism but without the adverse effects on insulin sensitivity (blood sugar) or cell proliferation (muscle growth) that is seen with unmodified HGH. Like unmodified GH, the HGH fragment 176-191 stimulates lipolysis (breaking down of fat) and inhibits lipogenesis (the formation of fatty acids and other lipids in the body).

HGH fragment 176-191 is meant to be 12.5 times stronger than human growth hormone (HGH) for weight loss than standard human growth hormone (HGH).

Of particular note is that in studies HGH fragment 176-191 had the ability to increase IGF-1 levels which translates into the fragments ability to give anti-aging effects.

How much Human Growth Hormone (HGH) Fragment 176-191 should be used?
In most studies favorable results have been shown with dosages between 400-600mcg or 4-6mcg/kg split into multiple dosages per day.

How long should Human Growth Hormone (HGH) Fragment 176-191 be used?
In most studies no adverse side effects were reported with continuous use per the dosage limits in the above answer.

What is a typical protocol for Human Growth Hormone (HGH) Fragment 176-191?
Studies have suggested the following:
A typical beginner protocol would be:
200mcg before breakfast
200mcg 30 minutes prior to training
Approximately 5-7 days a week – subcutaneous injections

A typical intermediate protocol would be:
250mcg before breakfast
250mcg 30 minutes prior to training
Approximately 5-7 days a week – subcutaneous injections

A typical advance protocol would be:
200mcg before breakfast
200mcg before lunch
200mcg 30 minutes prior to training
7 days a week – subcutaneous injections

When dosing multiple times a day at least 3 hours should separate the administrations.

What are some of the possible side effects with Human Growth Hormone (HGH) Fragment 176-191?
Reported side effects have included: hypersomnia (excessive sleeping), insomnia, burning feeling at injection spot (last 10-15 minutes). All side effects went away after 2-3 days of discontinuing use.

Should food be consumed before or after the injection of Human Growth Hormone (HGH) Fragment 176-191?
Studies have shown that administration should ideally be done on either an empty stomach or with only protein in the stomach. Fats and carbohydrates blunt growth hormone release. After administering the peptides wait at least 30 minutes to eat. At that point the growth hormone pulse has reached its peak and you can eat what you want.